Wednesday, May 6, 2009

Molecular pharming: Plants as bioreactors

"Niche pathway engineering for catechin biosynthesis in tea: Tea is grown in 31 countries across the globe and India is a major player in its export. Keeping in view the present global scenario, research on tea needed focus to meet the challenge of quality that supports health attributes. Tea has medicinal value due to its richness in polyphenols, wherein catechins are the most abundant. Catechins and their derivatives are responsible for astringency and bitterness of tea and taste. These are also important pharmaceutical compounds being strong antioxidants. While the biochemistry of catechin biosynthesis in tea is known, the control points and molecular aspects were not considered. To engineer the pathway for its desired modulation in the tea clones or in alternative crops of choice or to synthesise the flavonoids in vitro for use in pharmaceutical and other relevant industry, it is implicit to clone the niche-pathway genes from tea."
(Ed: V. L. Chopra, R. P. Sharma, S. R. Bhat, and B. M. Prasanna in 'Search for New Genes,' p. 218 Academic)

1 comment:

  1. You can recommend a book to identify some of these species?